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Thursday, June 20, 2013

Glyphosate formulations






Glyphosate formulations


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View the Evidence: Problem Substances

Acute poisoning with glyphosate-containing herbicides is approximately 7.7% from the available studies.

Pubmed Data : Clin Toxicol (Phila). 2010 Feb;48(2):129-36. PMID: 20136481
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : Chemical Exposure : CK(49) : AC(15)
Problem Substances : Glyphosate : CK(368) : AC(118)

Glyphosate can be detected in the urine of farmers and their families in farms where Roundup pesticide is used.

Pubmed Data : Environ Health Perspect. 2004 Mar;112(3):321-6. PMID: 14998747
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Problem Substances : Glyphosate : CK(368) : AC(118), Roundup (herbicide) : CK(365) : AC(116)

Glyphosate pesticide (Roundup) exposure is a risk factor for non-Hodgkin lymphoma and Hairy Cell leukemia.

Pubmed Data : Leuk Lymphoma. 2002 May;43(5):1043-9. PMID: 12148884
Article Published Date : May 01, 2002
Study Type : Human Study
Additional Links
Diseases : Hairy Leukoplakia : CK(10) : AC(2), Lymphoma : CK(209) : AC(69), Lymphoma: Non-Hodgkin : CK(256) : AC(67)
Problem Substances : Glyphosate : CK(368) : AC(118), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Carcinogen : CK(59) : AC(11)

Glyphosate pesticide (Roundup) exposure is a risk factor for non-Hodgkin lymphoma.

Pubmed Data : Int J Cancer. 2008 Oct 1;123(7):1657-63. PMID: 18623080
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Lymphoma: Non-Hodgkin : CK(256) : AC(67)
Problem Substances : Glyphosate : CK(368) : AC(118), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Carcinogen : CK(59) : AC(11)

Glyphosphate exposure has been linked to rhinitis among pesticide applicators.

Pubmed Data : J Toxicol Environ Health A. 2010;73(20):1382-93. PMID: 20818537
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Rhinitis : CK(20) : AC(1)
Problem Substances : Pesticides : CK(699) : AC(70), Roundup (herbicide) : CK(365) : AC(116)

Large scale bioenergy crop expansion results in levels of chemicals in the environment unsafe for human and ecological health.

Pubmed Data : Sci Total Environ. 2011 Aug 1 ;409(17):3215-29. Epub 2011 Jun 2. PMID: 21640371
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Additional Keywords : Bioenergy Crops : CK(10) : AC(1)
Problem Substances : Glyphosate : CK(368) : AC(118)

Multiple myeloma incidence among glyphosate-exposed pesticide applicators in the Agricultural Health Study appears to be higher.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2005 Jan ;113(1):49-54. PMID: 15626647
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Diseases : Multiple Myeloma : CK(156) : AC(53)
Problem Substances : Glyphosate : CK(368) : AC(118)

Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology.

Pubmed Data : Arch Toxicol. 2010 Apr;84(4):309-17. Epub 2009 Dec 12. PMID: 20012598
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hormonal Disorders: Children : CK(14) : AC(3), Pesticide Toxicity : CK(147) : AC(45), Testosterone: Too Low : CK(369) : AC(70)
Additional Keywords : Environmental Pollutant : CK(32) : AC(15)
Problem Substances : Glyphosate : CK(368) : AC(118), Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

There is evidence that there is a genotoxic risk potential associated with exposure to glyphosate in areas where the herbicide is applied.

Pubmed Data : J Toxicol Environ Health A. 2009;72(15-16):986-97. PMID: 19672767
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : DNA damage : CK(711) : AC(293)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

Cytogenetic damage and induction of pro-oxidant state has been observed in human lymphocytes exposed in vitro to glyphosate.

Pubmed Data : Environ Mol Mutagen. 1998 ;32(1):39-46. PMID: 9707097
Article Published Date : Jan 01, 1998
Study Type : Human In Vitro
Additional Links
Diseases : DNA damage : CK(711) : AC(293)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

Glyphosate adjuvants are not inactive, and exert cytotoxic effects at concentrations as low as 1 ppm.

Pubmed Data : Toxicology. 2012 Sep 21. Epub 2012 Sep 21. PMID: 23000283
Article Published Date : Sep 20, 2012
Study Type : Human In Vitro
Additional Links
Problem Substances : Ethoxylated adjuvants : CK(5) : AC(1), Glyphosate : CK(368) : AC(118), Glyphosate formulations : CK(386) : AC(121)
Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

The environmental metabolite of glyphosate, Aminomethylphosphonic acid, exhibits genotoxicity.

Pubmed Data : Ecotoxicol Environ Saf. 2009 Mar ;72(3):834-7. Epub 2008 Nov 14. PMID: 19013644
Article Published Date : Mar 01, 2009
Study Type : Human In Vitro
Additional Links
Diseases : DNA damage : CK(711) : AC(293), Liver Cancer : CK(1641) : AC(266)
Problem Substances : Aminomethylphosphonic acid : CK(12) : AC(5), Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Clastogenic : CK(6) : AC(2), Genotoxic : CK(146) : AC(61)

Acute glyphosate-surfactant poisoning with neurological sequels and fatal outcome

Pubmed Data : Vojnosanit Pregl. 2009 Sep ;66(9):758-62. PMID: 19877558
Article Published Date : Sep 01, 2009
Study Type : Human: Case Report
Additional Links
Diseases : Glyphosate Toxicity : CK(22) : AC(12)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Glyphosate-induced parkinsonism has been reported.

Pubmed Data : Mov Disord. 2001 May ;16(3):565-8. PMID: 11391760
Article Published Date : May 01, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Dopamine Levels: Low : CK(4) : AC(1), Glyphosate Toxicity : CK(22) : AC(12), Neurotoxicity : CK(37) : AC(15), Parkinsonian Disorders : CK(15) : AC(4), Substantia Nigra: Damage : CK(3) : AC(1)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Glyphosphate poisoning resulting in aseptic meningitis has been reported.

Pubmed Data : Clin Toxicol (Phila). 2011 Feb;49(2):118-20. PMID: 21370950
Article Published Date : Feb 01, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Meningitis: Aseptic : CK(3) : AC(1)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Measles vaccine and glyphosate-induced parkinsonism has been reported.

Pubmed Data : Arq Neuropsiquiatr. 2003 Jun ;61(2B):381-6. Epub 2003 Jul 28. PMID: 12894271
Article Published Date : Jun 01, 2003
Study Type : Human: Case Report
Additional Links
Diseases : Glyphosate Toxicity : CK(22) : AC(12), Parkinsonian Disorders : CK(15) : AC(4), Vaccine-induced Toxicity : CK(1130) : AC(163)
Anti Therapeutic Actions : Vaccination: Measles : CK(156) : AC(16)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Parkinsonism after chronic occupational exposure to glyphosate has been reported.

Pubmed Data : Parkinsonism Relat Disord. 2011 Jul;17(6):486-7. Epub 2011 Mar 2. PMID: 21367645
Article Published Date : Jul 01, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Parkinsonism : CK(12) : AC(8)
Problem Substances : Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

"Aminomethylphosphonic acid, a metabolite of glyphosate, causes injury in glyphosate-treated, glyphosate-resistant soybean."

Pubmed Data : J Agric Food Chem. 2004 Aug 11 ;52(16):5139-43. PMID: 15291487
Article Published Date : Aug 11, 2004
Study Type : Environmental
Additional Links
Problem Substances : Aminomethylphosphonic acid : CK(12) : AC(5), Glyphosate : CK(368) : AC(118)

"Changes in the dissipation or distribution of glyphosate following repeated applications of glyphosate may be related to shifts in the soil microbial community composition."

Pubmed Data : Pest Manag Sci. 2010 Jan ;66(1):59-64. PMID: 19697445
Article Published Date : Jan 01, 2010
Study Type : Environmental
Additional Links
Additional Keywords : Ecotoxicology: Glyphosate : CK(17) : AC(9)
Problem Substances : Glyphosate : CK(368) : AC(118)

"Direct determination of glyphosate and its major metabolite, aminomethylphosphonic acid, in fruits and vegetables by mixed-mode hydrophilic interaction/weak anion-exchange liquid chromatography coupled with electrospray tandem mass spectrometry."

Pubmed Data : J Chromatogr A. 2012 Dec 3. Epub 2012 Dec 3. PMID: 23261284
Article Published Date : Dec 02, 2012
Study Type : Environmental
Additional Links
Problem Substances : Aminomethylphosphonic acid : CK(12) : AC(5), Glyphosate : CK(368) : AC(118)

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